Our gut microbiome may have affected by several factors like antibiotics, poor diet, or
traveling. But supplemental probiotics, consumed naturally or in supplement form, can help
restore a healthy gut microbiome (Amara and Shibl, 2015). Probiotic supplements generally
support immune function, digestion, nutrition absorption and can decrease the risk or duration
of common infections, including those of the respiratory tract and gut (Zhang et al., 2018, Slam,
2016). Scientists established certain types of best probiotics supplements which support
women’s gut and digestive health. Probiotics may also support reproductive health by
balancing the vaginal microbiome. These “friendly bacteria” tend to alleviate bacterial
vaginosis and pathogens in the urinary tract and balance the pH environment in the vagina.
Benefits of probiotics supplements: .
Probiotic supplements provide numerous benefits because they contain live microorganisms, such as bacteria or yeast, which support the healthy bacteria in your gut. It is note that minimum potency or cfu required to get benefits from probiotic supplements. It is recommended that 100 million to 1 billion probiotic microorganisms must reach your intestine for you to experience health benefits (Gagliardi et al., 2018).
How to choose the best probiotic supplements for women?
Probiotic supplements which considered as best for women only if it is contains extensively researched potential probiotic strains such as Lacticaseibacillus rhamnosus, Lactobacillus acidophilus, Lactiplantibacillus plantarum, Limosilactobacillus fermentum, Bifidobacterium longum, Bifidobacterium bifidum, Saccharomyces boulardii etc. which has been shown to support the vaginal health, promote immunity and ease symptoms of IBS.
Moreover, when selecting the best probiotic supplements for women, take into account some important points like the price, CFU (colony forming units) which should be not less than 1 Billion, probiotic strains, formulation which should be Vegan, allergen-free, delayed-release capsules etc. It also necessary to consider the brand name and probiotic suppliers to ensure about the quality and bioavailability of the product.
Best 9 probiotics supplements for women:
There are various probiotic supplements are available which are marketed by different national and international probiotic suppliers. Based on the important selection criteria, here we have selected 9 best probiotic supplements for women. These probiotic supplements are effective for women suffering from IBS (irritable bowel syndrome), bacterial vaginosis, urinary tract infection and supportive vaginal and digestive health in women over 50 years of age.
- Ritual’s Synbiotic + : best probiotics for women’s gut health:-
Ritual’s Synbiotic+ is the best probiotic and prebiotic formulation for gut health, including the two most clinically studied strains of probiotics: Lacticaseibacillus rhamnosus and Bifidobacterium animalis. The viability of the probiotics is enhanced with the delayed-release and vegan capsules containing 11 billion CFU. Independent lab testing ensures that the product is non-GMO, major allergen-free, and have enhanced traceability. The Synbiotic+ probiotics are shelf-stable.
Besides the main active bacteria, Synbiotic+ also contains 15 mg of prebiotics and 300 mg of postbiotics. These additional ingredients help alleviate oxidative stress and gut inflammation. It is generally available in the market of USA, UK, and Canada. Packing a three-in-one blend of prebiotics, probiotics, and postbiotics, this supplement is intended to promote the health of women’s gut microbiome, support relief of occasional discomforts such as mild and occasional bloating, gas, diarrhea and support a balanced gut microbiome. It contains Bifidobacterium animalis ssp. lactis, a probiotic strain that has been shown to help strengthen the gut barrier and promote regularity (Cheng et al., 2021). It also contains Lacticaseibacillus rhamnosus, which can reduce several symptoms of IBS, including bloating and stomach pain (Ceccherini et al., 2022). - Culturelle Women's Healthy Balance Probiotic Capsules:
- Ora — best probiotics provider for women's vaginal and digestive health
- HUM private Party:
- Bio-Kult Pro Cyan: Probiotic supplement targeting Urinary Tract
- Renew Life Probiotics for Women - 25 Billion CFU:
- OLLY Probiotic + Prebiotic Gummy: Digestive Support and Gut Health:
- Garden of Life Once Daily Women's Probiotic Capsules: Dr. Formulated Probiotics for Women’s Daily Digestive Vaginal & Immune Health:
- Super Smart — best probiotics for weight loss:
Culturelle - Women's Health Balance capsules are the best to manage bacterial vaginosis while
balancing the pH environment in the vagina. It women’s 4-in-1 Protection, Daily Probiotics for
Vaginal Health, Digestive Health, & Immune Support. It contains Probiotics 15 billion
CFU and are created with 5 clinically proven strains including Lactobacillus
rhamnosus GG for balancing women’s health as well as maintain a healthy balance of good
bacteria in the women’s body. Culturelle contains 10 billion Colony Forming Units of probiotic
strains, combines 200 mg of inulin. It’s one of the best probiotics for women’s pH balance,
which can support multiple aspects of health.
Culturelle Probiotics meets the highest standards for purity and potency. It also helps maintain
an optimal balance of good bacteria in the body (Capurso, 2019). Culturelle’s capsules are
vegan, gluten, soy, nut, and dairy-free. These probiotics do not need refrigeration. This
supplements are available in the market of USA, Brazil, Canada, Europe, and Asia. Culturelle’s
capsules are vegan, gluten, soy, nut, and dairy-free.
Ora’s Lady bugs probiotics are the best for women's vaginal and digestive health. It contains
16 Billion Probiotics, 6 Strains chosen to Support Women's Health including Lacticaseibacillus
rhamnosus, Lactobacillus crispatus, Lactiplantibacillus plantarum, and Limosilactobacillus
fermentum to provide vaginal health support with ingredients that can aid in rebalancing the
microbiome, support natural protection against harmful bacteria, and restoring vaginal flora.
To fortify the effectiveness of these probiotics, Ora added plant-based Organic Prebiotics,
made from Organic Jerusalem Artichoke. Prebiotics are the food that probiotics need to
survive.
Selected strains are known to support a normal and healthy response to digestive issues
like bloating, stomach pain, and poor nutrient absorption. Probiotic strains
including Lactobacillus acidophilus and Lactiplantibacillus plantarum, have even been shown
to reduce inflammation in human and animal studies (Kim et al., 2019; Park et al., 2018; Zhao
et al., 2021). Lactiplantibacillus plantarum may increase the amount of beneficial bacteria in
the vagina, which could help prevent yeast infections (Vladareanu et al.,2021). Ora’s Lady
bugs probiotics are free from preservatives, GMOs, sugar, tree nuts, dairy, and artificial colors.
This probiotics supplement need no refrigeration.
This probiotic supplement helps to support vaginal health and urinary tract health. It contains
a three potent vaginal probiotic strains and cranberry to help balance the vaginal microbiome
and promote optimal urinary tract function. With three strains of probiotics and cranberry
extract, HUM Nutrition Private Party is good for promoting pH balance and supporting the
health of your vaginal microbiome.
HUM Nutrition Private Party contains Lactobacillus acidophilus which is well studied for its
ability to protect against vaginal pathogens to prevent issues like chronic vaginitis (Chee et al.,
2020). It also contains Lacticaseibacillus rhamnosus and Limosilactobacillus reuteri, which
may help reduce the growth of harmful fungi and bacteria in the vagina, according to some
test-tube and animal studies (Jorgensen et al., 2020; Shazadi et al., 2021).
Bio-Kult Pro-Cyan is a triple action probiotic formulation scientifically developed with
cranberry extract, two specifically-selected probiotic strains & vitamin A to support the health
of the urinary tract and protect against infections. It is an advanced bacterial formulation which
contains potential probiotic strains of Lactobacillus acidophilus PXN 35 and
Lactiplantibacillus plantarum PXN 47. Bio-Kult Pro-Cyan is Vegan, Non – GMO and proven
to survive the high acidity of the stomach.
Lactobacillus acidophilus and Lactiplantibacillus plantarum, both of which have
antimicrobial properties and could help block the growth of E. coli, a type of bacteria that often
causes urinary tract infections (Kumar et al., 2016). Research also suggests that Lactobacillus
acidophilus could promote vaginal health and protect against conditions such as bacterial
vaginosis (Bertuccini et al., 2017; Reznichenkoet al., 2020).
Renew Life Probiotic with 25 billion potency of cultures from 12 specially selected strains, this women’s probiotic helps digestive health. This probiotic supplement made clinically tested strains shown to balance healthy pH and yeast levels, and includes the potent Lactobacillus acidophilus to support vaginal health. It contains probiotic strains along with highest quality global ingredients, and is gluten free, dairy free and soy free. For this ultimate flora probiotic supplement for women, refrigeration is recommended, but not required. It also contains probiotic strains, including Limosilactobacillus reuteri and Lactiplantibacillus rhamnosus, that may help enhance the health of the vaginal microbiome (Liu et al., 2020).
OLLY PROBIOTIC + PREBIOTIC: These chewable adult probiotics deliver a powerful combination of live Probiotics and Prebiotic Fiber to help keep your natural flora and digestion balance. It contains 500 million CFU of Bacillus coagulans work with your body’s natural bacteria to support a healthy digestive tract and immune system. These probiotic & prebiotic gummies come in naturally flavored Peachy Peach with no artificial colors or flavors and are gluten free. This supplements contain a probiotic strain that has been shown to reduce symptoms and improve quality of life for people with IBS (Gupta and Maity, 2021); Madempudi et al., 2019).
Garden of Life contains 16 potential probiotic strains for digestive health along with effective
prebiotic. Garden of Life once daily women’s probiotic supplement is doctor formulated for
women's specific health needs, promoting her health with vaginal probiotics. It contains strains
of Limosilactobacillus reuteri and Limosilactobacillus fermentum which were clinically
studied for vaginal health.
Each serving contains 16 strains of probiotics and 50 billion colony-forming units
(CFU) and it is shelf stable, easy-to-swallow vegetarian capsule. It is Non GMO, NSF Gluten
Free and Carbon Neutral and Dairy and Soy Free. It contains potential strains of
Lacticaseibacillus rhamnosus, Lactobacillus brevis and Lactobacillus acidophilus, which may
be beneficial to treat and prevent infections such as bacterial vaginosis (Bertuccini et al., 2017;
Reznichenko et al., 2020).
This supplement is shelf-stable and certified gluten-free by NSF International. The
product contains prebiotics which may intensify digestive symptoms in some people, such as
those with irritable bowel syndrome (IBS), though the research is mixed (Davari et al., 2019).
Some studies also suggest that having multiple strains of probiotics in a supplement could
enhance the biological activity of the probiotics, other research has found that multi-strain
supplements are not significantly more effective than single-strain probiotics (Kwoji et al.,
2021; McFarland,2020).
Super Smart probiotics are ideal for weight management as they are formulated
with Lactobacillus gasseri, known to help weight loss by combating abdominal fat
accumulation.
The probiotic strains present in Super Smart are vegetarian and free of nanoparticles,
GMOs, and gluten. Also, the probiotics are produced in FDA, GMP, and HACCP-certified
facilities. Super Smart’s Lactobacillus gasseri contain 6 billion CFU from a single strain. The
bottle should be refrigerated. This probiotic supplement is available in the market of USA,
Canada, and Mexico.
CONCLUSION
Probiotics can benefit women in specific ways. Best probiotic supplements to take depends on the specific needs and goals of the women. Some women may prefer supplements that focus on improving vaginal health or supporting pH balance, others may prefer a probiotic with specific strains that can promote digestive health or boost immunity. Therefore, while selecting the right probiotics, it is crucial to consider the potential bacteria strains in the probiotics. Probiotic supplements have also been vetted to ensure that they meet standard of quality and adhere to Food and Drug Administration (FDA) regulations on allowable health claims and labelling requirements, and are manufactured in facilities that adhere to Current Good Manufacturing Practices (CGMPs) established by the FDA.
References:
-
Amara A.A and Shibl A. (2015): Role of Probiotics in Health Improvement, Infection Control and Disease Treatment and Management. Saudi Pharm J. Vol.23(2), pp-107-114.
-
Zhang H., Yeh C., Jin Z., et al. (2018): Prospective study of probiotic supplementation results in immune stimulation and improvement of upper respiratory infection rate. Synth Syst Biotechnol. Vol.3(2), pp-113-120.
-
Islam SU (2016). Clinical Uses of Probiotics. Medicine (Baltimore). Vol.95(5): e2658.
-
Gagliardi A., Totino V., Cacciotti F., Iebba V., Neroni B., Bonfiglio G., Trancassini M., Passariello C., Pantanella F., Schippa S. (2018): Rebuilding the Gut Microbiota Ecosystem. Int J Environ Res Public Health. Vol.7;15(8), pp-1679.
-
Cheng J., Laitila A., Ouwehand A.C. (2021): Bifidobacterium animalis subsp. lactis HN019 Effects on Gut Health: A Review. Front Nutr. 14; 8:790561. doi: 10.3389/fnut.2021.790561.
-
Ceccherini C., Daniotti S., Bearzi C., Re I. (2022): Evaluating the Efficacy of Probiotics in IBS Treatment Using a Systematic Review of Clinical Trials and Multi-Criteria Decision Analysis. Nutrients. Vol.14(13):2689. doi: 10.3390/nu14132689. PMID: 35807868; PMCID.
-
Capurso L. (2019): Thirty Years of Lactobacillus rhamnosus GG: A Review. J Clin Gastroenterol. Suppl 1: S1-S41. doi: 10.1097/MCG.0000000000001170. PMID: 30741841.
-
Kim D.H, Kim S., Lee J.H., Kim J.H., Che X., Ma H.W., Seo D.H, Kim T.I., Kim W.H, Kim S.W., Cheon J.H. (2019): Lactobacillus acidophilus suppresses intestinal inflammation by inhibiting endoplasmic reticulum stress. J Gastroenterol Hepatol.Vol.34(1):178-185.
-
Park J.S., Choi J.W., Jhun J., Kwon J.Y., Lee B.I, Yang C.W., Park S.H., Cho M.L. (2018): Lactobacillus acidophilus Improves Intestinal Inflammation in an Acute Colitis Mouse Model by Regulation of Th17 and Treg Cell Balance and Fibrosis Development. J Med Food. Vol.21(3):215-224.
-
Zhao W., Peng C., Sakandar H.A., Kwok L.Y., Zhang W. (2021): Meta-Analysis: Randomized Trials of Lactobacillus plantarum on Immune Regulation Over the Last Decades. Front Immunol. Vol.22;12:643420.
-
Vladareanu R., Mihu D., Mitran M., Mehedintu C., Boiangiu A., Manolache M., Vladareanu S. (2018): New evidence on oral L. plantarum P17630 product in women with history of recurrent vulvovaginal candidiasis (RVVC): a randomized double-blind placebo controlled study. Eur Rev Med Pharmacol Sci. Vol.22(1):262-26
-
Chee W.J.Y, Chew S.Y., Than L.T.L (2020): Vaginal microbiota and the potential of Lactobacillus derivatives in maintaining vaginal health. Microb Cell Fact. Vol.19(1):203.
-
Rose Jorgensen M., Thestrup Rikvold P, Lichtenberg M., Østrup Jensen P., Kragelund C., Twetman S. (2020): Lactobacillus rhamnosus strains of oral and vaginal origin show strong antifungal activity in vitro. J Oral Microbiol. Vol.12(1):1832832.
-
Shazadi K., Ahmad S.Z., Ahmad S.S., Arshad N. (2021): In vivo prophylactic efficacy of Lactobacillus reuteri MT180537 against aerobic vaginitis. Microb Pathog. 160:105197. doi: 10.1016/j.micpath.2021.105197.
-
Kumar M., Dhaka P., Vijay D., Vergis J., Mohan V., Kumar A., Kurkure N.V., Barbuddhe S.B, Malik S.V, Rawool D.B. (2016): Antimicrobial effects of Lactobacillus plantarum and Lactobacillus acidophilus against multidrug-resistant enteroaggregative Escherichia coli. Int J Antimicrob Agents. Vol.48(3):265-70.
-
Bertuccini L., Russo R., Iosi F., Superti F. (2017): Effects of Lactobacillus rhamnosus and Lactobacillus acidophilus on bacterial vaginal pathogens. Int J Immunopathol Pharmacol. Vil. 30(2):163-167.
-
Reznichenko H., Henyk N., Maliuk V, Khyzhnyak T., Tynna Y., Filipiuk I., Veresniuk N., Zubrytska L., Quintens J., Richir K., Gerasymov S. (2020): Oral Intake of Lactobacilli Can Be Helpful in Symptomatic Bacterial Vaginosis: A Randomized Clinical Study. J Low Genit Tract Dis. Vol.24(3):284-289.
-
Liu Y., Huang Y., Cai W., Li D., Zheng W., Xiao Y., Liu Y., Zhao H., Pan S. (2020): Effect of oral Lactobacillusrhamnosus GR-1 and Lactobacillusreuteri RC-14 on vaginal Group B Streptococcus colonization and vaginal microbiome in late pregnancy]. Nan Fang Yi Ke Da Xue Xue Bao. Vol.40(12):1753-1759.
-
Gupta A.K and Maity C. (2021): Efficacy and safety of Bacillus coagulans LBSC in irritable bowel syndrome: A prospective, interventional, randomized, double-blind, placebo controlled clinical study [CONSORT Compliant]. Medicine (Baltimore). Vol.100(3):e23641.
-
Madempudi R.S, Ahire J.J, Neelamraju J., Tripathi A., Nanal S. (2019): Randomized clinical trial: the effect of probiotic Bacillus coagulans Unique IS2 vs. placebo on the symptoms management of irritable bowel syndrome in adults. Sci Rep. Vol. 9(1):12210.
-
Davani-Davari D., Negahdaripour M., Karimzadeh I, Seifan M., Mohkam M., Masoumi S.J., Berenjian A, Ghasemi Y. (2019): Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications. Foods. Vol.8(3):92.
-
Kwoji I.D, Aiyegoro O.A, Okpeku M., Adeleke M.A. (2021): Multi-Strain Probiotics: Synergy among Isolates Enhances Biological Activities. Biology (Basel). Vol.10(4):322.
-
McFarland L.V. (2020): Efficacy of Single-Strain Probiotics Versus Multi-Strain Mixtures: Systematic Review of Strain and Disease Specificity. Dig Dis Sci. Vol.66(3):694-704.